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| Other Studies - Cell Cycle Progression The
progression of cells through the cell cycle can be impaired
by environmental stress. Higashikubo and colleagues (2001) examined
cell cycle progression following exposure to RF fields, because
"cancer is disease of impaired cell growth control, and
the regulation of cell cycle progression is an essential component
of this process". There was no evidence of any disturbance
of the cell cycle progression in their study. In contrast,
Cleary et al. (1996) found the rate of cell cycle progression
to be increased following 12 hours of exposure to 2.45 GHz
RFR at 5 or 25 W/kg. Capri (2004b) found that exposure to
900 MHz RFR had no effect on cell cycle phases. Takashima
(2006), however, found no effect of RFR at 2.45 GHz frequency
on cell proliferation at SARs up to 200 W/kg. At 200 W/kg
or more cell growth and survival were affected, and the effects
appeared to be thermal in nature. Lantow (2006) found no
evidence of altered cell cycle kinetics in human Mono Mac
6 cells exposed to RFR from an 1800 MHz GSM-DTX signal for
12 hours. Chauhan (2007) also found no change in cell cycle
kinetics in TK6, HL60, or Mono-Mac-6 cells exposed to 1.9
GHz RFR for 6 hours at 0, 1, or 10 W/kg. Buttiglione (2007) reported that short-term exposure to 900
MHz RFR affect expression of the gene Egr-1 and cell regulatory
functions. Authors Authors
Authors Authors
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